Bakuchiol is a novel meroterpenoid (bioactive that serves as a natural secondary metabolite) found in the seeds and leaves of the babchi flower. Comparative gene expression profiling reveals that topical bakuchiol can operate as a functional analog of topical retinol in vitro, mimicking the biological functions and effects of retinol but through a secondary mechanistic pathway. Although bakuchiol is structurally different to retinol, it can bind to the same nuclear retinoic acid receptors (RARs) that regulate cell turnover.

Linoleic acid is an omega-6 fatty acid (found in sunflower) that serves as an essential fatty acid that the human body cannot produce on its own. It serves the skin barrier as a structural precursor for important skin lipids called ceramides (connecting end-to-end to form a lipid bilayer - the fundamental structural component of cell membranes that acts as a selective barrier and the skin’s primary defense system)

Salicylic acid was discovered from studying the phytochemical profile of willow bark (different than willowherb but still interesting) - In 1828, Rafael Piria, an Italian chemist, successfully isolated salicin from the bark of the white willow tree, which upon metabolization is converted to salicylic acid. With subsequent research, salicylic acid’s keratolytic (exfoliating) properties were discovered when scientists experimented with its topical application on hyperkeratotic conditions (warts, calluses, etc.) and observed its ability to break down and dissolve excess keratin, resulting in the exfoliation of dead skin cells.

Salicylic acid was discovered from studying the phytochemical profile of willow bark (different than willowherb but still interesting) - In 1828, Rafael Piria, an Italian chemist, successfully isolated salicin from the bark of the white willow tree, which upon metabolization is converted to salicylic acid. With subsequent research, salicylic acid’s keratolytic (exfoliating) properties were discovered when scientists experimented with its topical application on hyperkeratotic conditions (warts, calluses etc.) and observed its ability to break down and dissolve excess keratin, resulting in the exfoliation of dead skin cells.

Bakuchiol is a novel meroterpenoid (bioactive that serves as a natural secondary metabolite) found in the seeds and leaves of the babchi flower. Comparative gene expression profiling reveals that topical bakuchiol can operate as a functional analog of topical retinol in vitro, mimicking the biological functions and effects of retinol but through a secondary mechanistic pathway. Although bakuchiol is structurally different to retinol, it can bind to the same nuclear retinoic acid receptors (RARs) that regulate cell turnover.

Precision indoor farming is an advancement of agronomic R&D that uses controlled inputs to optimize the biomass and phytochemical composition of plants, maximizing active yield and the stability of its active composition.